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Effects may be faster with medical-grade B12 and professional dosing

B12 also supports red blood cell formation, preventing megaloblastic anemiaa cause of fatigue and weakness

While toxicity is rare, excessive intake of certain B vitamins (particularly B or B) from multiple sources could increase the risk of side effects (like niacin flush or peripheral neuropathy)

Oral absorption is considered too undependable to rely on in patients with pernicious anemia or other conditions resulting in malabsorption of Vitamin B12

Because it is an unstudied compound in humans, cautious researchers treat it as experimental across the board